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Therapeutic efficacy evaluation of radioimmunotherapy with (90)Y‐labeled anti‐podoplanin antibody NZ‐12 for mesothelioma

Podoplanin is a type I transmembrane sialomucin‐like glycoprotein that is highly expressed in malignant mesothelioma. The rat‐human chimeric antibody NZ‐12 has high affinity for human podoplanin and antibody‐dependent cellular cytotoxicity and is applicable for radioimmunotherapy (RIT) to enhance th...

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Detalles Bibliográficos
Autores principales: Sudo, Hitomi, Tsuji, Atsushi B., Sugyo, Aya, Saga, Tsuneo, Kaneko, Mika K., Kato, Yukinari, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500970/
https://www.ncbi.nlm.nih.gov/pubmed/30801908
http://dx.doi.org/10.1111/cas.13979