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Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer

Y‐box binding protein‐1 (YBX1), a multifunctional oncoprotein containing an evolutionarily conserved cold shock domain, dysregulates a wide range of genes involved in cell proliferation and survival, drug resistance, and chromatin destabilization by cancer. Expression of a multidrug resistance‐assoc...

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Detalles Bibliográficos
Autores principales: Kuwano, Michihiko, Shibata, Tomohiro, Watari, Kosuke, Ono, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500994/
https://www.ncbi.nlm.nih.gov/pubmed/30903644
http://dx.doi.org/10.1111/cas.14006