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Hypoxia/pseudohypoxia‐mediated activation of hypoxia‐inducible factor‐1α in cancer

Since the first identification of hypoxic cells in sections of carcinomas in the 1950s, hypoxia has been known as a central hallmark of cancer cells and their microenvironment. Indeed, hypoxia benefits cancer cells in their growth, survival, and metastasis. The historical discovery of hypoxia‐induci...

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Detalles Bibliográficos
Autores principales: Hayashi, Yoshihiro, Yokota, Asumi, Harada, Hironori, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501028/
https://www.ncbi.nlm.nih.gov/pubmed/30844107
http://dx.doi.org/10.1111/cas.13990