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Testis‐specific protein, Y‐linked 1 activates PI3K/AKT and RAS signaling pathways through suppressing IGFBP3 expression during tumor progression

The testis‐specific protein, Y‐linked 1 (TSPY1), a newly recognized cancer/testis antigen, has been suggested to accelerate tumor progression. However, the mechanisms underlying TSPY1 cancer‐related function remain limited. By mining the RNA sequencing data of lung and liver tumors from The Cancer G...

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Detalles Bibliográficos
Autores principales: Tu, Wenling, Yang, Bo, Leng, Xiangyou, Pei, Xue, Xu, Jinyan, Liu, Mohan, Dong, Qiang, Tao, Dachang, Lu, Yongjie, Liu, Yunqiang, Yang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501036/
https://www.ncbi.nlm.nih.gov/pubmed/30815935
http://dx.doi.org/10.1111/cas.13984