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Targeting HOX/PBX dimer formation as a potential therapeutic option in esophageal squamous cell carcinoma

Homeobox genes are known to be classic examples of the intimate relationship between embryogenesis and tumorigenesis, which are a family of transcriptional factors involved in determining cell identity during early development, and also dysregulated in many malignancies. Previously, HOXB7, HOXC6 and...

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Detalles Bibliográficos
Autores principales: Shen, Lu‐Yan, Zhou, Ting, Du, Ya‐Bing, Shi, Qi, Chen, Ke‐Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501045/
https://www.ncbi.nlm.nih.gov/pubmed/30844117
http://dx.doi.org/10.1111/cas.13993