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Associations between rare microglia-linked Alzheimer's disease risk variants and subcortical brain volumes in young individuals

INTRODUCTION: Recent exome sequencing studies have identified three novel risk variants associated with Alzheimer's disease (AD). However, the mechanisms by which these variants confer risk are largely unknown. METHODS: In the present study, the impact of these rare coding variants (in ABI3, PL...

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Detalles Bibliográficos
Autor principal: Lancaster, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501059/
https://www.ncbi.nlm.nih.gov/pubmed/31080872
http://dx.doi.org/10.1016/j.dadm.2019.03.005