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Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli

Metabolic engineering requires fine-tuned gene expression for most pathway optimization applications. To develop a suitable suite of promoters, traditional bacterial promoter engineering efforts have focused on modifications to the core region, especially the −10 and −35 regions, of native promoters...

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Detalles Bibliográficos
Autores principales: Presnell, Kristin V., Flexer-Harrison, Madeleine, Alper, Hal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501063/
https://www.ncbi.nlm.nih.gov/pubmed/31080900
http://dx.doi.org/10.1016/j.synbio.2019.04.002