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Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli
Metabolic engineering requires fine-tuned gene expression for most pathway optimization applications. To develop a suitable suite of promoters, traditional bacterial promoter engineering efforts have focused on modifications to the core region, especially the −10 and −35 regions, of native promoters...
Autores principales: | Presnell, Kristin V., Flexer-Harrison, Madeleine, Alper, Hal S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501063/ https://www.ncbi.nlm.nih.gov/pubmed/31080900 http://dx.doi.org/10.1016/j.synbio.2019.04.002 |
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