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Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation
Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex. CRBN was originally reported as a gene associated with autosomal recessive non-syndromic mild menta...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501120/ https://www.ncbi.nlm.nih.gov/pubmed/31055217 http://dx.doi.org/10.1016/j.isci.2019.04.007 |