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Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain

Rett syndrome is a rare neuropsychiatric disorder with a wide symptomatology including impaired communication and movement, cardio-respiratory abnormalities, and seizures. The clinical presentation is typically associated to mutations in the gene coding for the methyl-CpG-binding protein 2 (MECP2),...

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Detalles Bibliográficos
Autores principales: Sanfeliu, Albert, Hokamp, Karsten, Gill, Michael, Tropea, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501143/
https://www.ncbi.nlm.nih.gov/pubmed/31110484
http://dx.doi.org/10.3389/fpsyt.2019.00278