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The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

Interleukin-10 (IL-10) is a key anti-inflammatory cytokine, secreted by macrophages and other immune cells to attenuate inflammation. Autocrine type I interferons (IFNs) largely mediate the delayed expression of IL-10 by LPS-stimulated macrophages. We have previously shown that IL-10 is synergistica...

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Detalles Bibliográficos
Autores principales: Ernst, Orna, Glucksam-Galnoy, Yifat, Athamna, Muhammad, Ben-Dror, Iris, Ben-Arosh, Hadar, Levy-Rimler, Galit, Fraser, Iain D. C., Zor, Tsaffrir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501241/
https://www.ncbi.nlm.nih.gov/pubmed/31148944
http://dx.doi.org/10.1155/2019/3451461