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The Adverse Effects of Thyrotropin Absence on Pancreatic β Cell Function in Mice

Thyrotropin (TSH) is a modulator of glucose metabolism by binding to its receptor on pancreatic cells. We used thyrotropin receptor (TSHR) knockout mice (Tshr(−/−)) as a model of TSH deletion to study its function in pancreatic β cells. Tshr(−/−) mice had a similar body weight at birth compared with...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Chen, Yu, Chen, Jie, Zhang, Danyu, Wang, Jianhua, Mao, Xiaodong, Wei, Xiao, Li, Xingjia, Ma, Xianghua, Liu, Chao, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501250/
https://www.ncbi.nlm.nih.gov/pubmed/31179344
http://dx.doi.org/10.1155/2019/9536032