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The Adverse Effects of Thyrotropin Absence on Pancreatic β Cell Function in Mice
Thyrotropin (TSH) is a modulator of glucose metabolism by binding to its receptor on pancreatic cells. We used thyrotropin receptor (TSHR) knockout mice (Tshr(−/−)) as a model of TSH deletion to study its function in pancreatic β cells. Tshr(−/−) mice had a similar body weight at birth compared with...
Autores principales: | Yang, Yu, Chen, Yu, Chen, Jie, Zhang, Danyu, Wang, Jianhua, Mao, Xiaodong, Wei, Xiao, Li, Xingjia, Ma, Xianghua, Liu, Chao, Wang, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501250/ https://www.ncbi.nlm.nih.gov/pubmed/31179344 http://dx.doi.org/10.1155/2019/9536032 |
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