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Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy

BACKGROUND: Immune checkpoint therapies (ICTs) targeting the programmed cell death-1 (PD1)/programmed cell death ligand-1 (PD-L1) pathway have improved outcomes for patients with non-small cell lung cancer (NSCLC), particularly those with high PD-L1 expression. However, the predictive value of manua...

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Detalles Bibliográficos
Autores principales: Althammer, Sonja, Tan, Tze Heng, Spitzmüller, Andreas, Rognoni, Lorenz, Wiestler, Tobias, Herz, Thomas, Widmaier, Moritz, Rebelatto, Marlon C., Kaplon, Helene, Damotte, Diane, Alifano, Marco, Hammond, Scott A., Dieu-Nosjean, Marie-Caroline, Ranade, Koustubh, Schmidt, Guenter, Higgs, Brandon W., Steele, Keith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501300/
https://www.ncbi.nlm.nih.gov/pubmed/31060602
http://dx.doi.org/10.1186/s40425-019-0589-x