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Similar incidence of DNA damage response pathway alterations between clinically localized and metastatic prostate cancer
BACKGROUND: In this era of precision medicine, the DNA damage response (DDR) pathway has been shown to be a viable target of intervention in metastatic castration-resistant prostate cancer (CRPC) as approximately one-third of CRPC patients harbor DDR pathway mutations. To determine whether DDR pathw...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501301/ https://www.ncbi.nlm.nih.gov/pubmed/31060606 http://dx.doi.org/10.1186/s12894-019-0453-9 |