Similar incidence of DNA damage response pathway alterations between clinically localized and metastatic prostate cancer

BACKGROUND: In this era of precision medicine, the DNA damage response (DDR) pathway has been shown to be a viable target of intervention in metastatic castration-resistant prostate cancer (CRPC) as approximately one-third of CRPC patients harbor DDR pathway mutations. To determine whether DDR pathw...

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Detalles Bibliográficos
Autores principales: Kim, Isaac E., Kim, Sinae, Srivastava, Arnav, Saraiya, Biren, Mayer, Tina, Kim, Wun-Jae, Kim, Isaac Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501301/
https://www.ncbi.nlm.nih.gov/pubmed/31060606
http://dx.doi.org/10.1186/s12894-019-0453-9

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