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Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein

BACKGROUND: Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of the human genome sequence. These mobile elements are able to copy themselves wit...

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Detalles Bibliográficos
Autores principales: Freeman, B. T., Sokolowski, M., Roy-Engel, A. M., Smither, M. E., Belancio, V. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501352/
https://www.ncbi.nlm.nih.gov/pubmed/31080522
http://dx.doi.org/10.1186/s13100-019-0159-2