Cargando…

Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein

BACKGROUND: Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of the human genome sequence. These mobile elements are able to copy themselves wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Freeman, B. T., Sokolowski, M., Roy-Engel, A. M., Smither, M. E., Belancio, V. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501352/ https://www.ncbi.nlm.nih.gov/pubmed/31080522 http://dx.doi.org/10.1186/s13100-019-0159-2

Ejemplares similares

The RNA Polymerase Dictates ORF1 Requirement and Timing of LINE and SINE Retrotransposition
por: Kroutter, Emily N., et al.
Publicado: (2009)

The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations
por: Kines, Kristine J., et al.
Publicado: (2016)

Characterization of L1 ORF1p Self-Interaction and Cellular Localization Using a Mammalian Two-Hybrid System
por: Sokolowski, Mark, et al.
Publicado: (2013)

Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)
por: Christian, Claiborne M., et al.
Publicado: (2016)

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans
por: Sokolowski, Mark, et al.
Publicado: (2017)

The importance of L1 ORF2p cryptic sequence to ORF2p fragment-mediated cytotoxicity
por: Christian, Claiborne M., et al.
Publicado: (2016)

Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein
por: Sokolowski, Mark, et al.
Publicado: (2014)

A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis
por: Du, Qianhui, et al.
Publicado: (2023)

Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci
por: Kines, Kristine J., et al.
Publicado: (2014)

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p
por: Khazina, Elena, et al.
Publicado: (2018)

Identification of Nuclear Localization Signals in the ORF2 Protein of Porcine Circovirus Type 3
por: Mou, Chunxiao, et al.
Publicado: (2019)

Somatic expression of LINE-1 elements in human tissues
por: Belancio, Victoria P., et al.
Publicado: (2010)

A comprehensive approach to expression of L1 loci
por: Deininger, Prescott, et al.
Publicado: (2017)

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition
por: Servant, Geraldine, et al.
Publicado: (2017)

In vivo RNA localization of I factor, a non-LTR retrotransposon, requires a cis-acting signal in ORF2 and ORF1 protein
por: del Carmen Seleme, Maria, et al.
Publicado: (2005)

Molecular Reconstruction of Extinct LINE-1 Elements and Their Interaction with Nonautonomous Elements
por: Wagstaff, Bradley J., et al.
Publicado: (2013)

Identification of Critical Regions in Human SAMHD1 Required for Nuclear Localization and Vpx-Mediated Degradation
por: Guo, Haoran, et al.
Publicado: (2013)

Serum levels of L1-ORF1p and airflow limitation
por: Guerra, Stefano, et al.
Publicado: (2019)

Norovirus Recombination in ORF1/ORF2 Overlap
por: Bull, Rowena A., et al.
Publicado: (2005)

LINE dancing in the human genome: transposable elements and disease
por: Belancio, Victoria P, et al.
Publicado: (2009)

The conserved multi-functional nuclear protein dss-1/Sem1 is required for C9orf72-associated ALS/FTD dipeptide toxicity
por: Puleo, Noah, et al.
Publicado: (2020)

A single amino acid substitution in ORF1 dramatically decreases L1 retrotransposition and provides insight into nucleic acid chaperone activity
por: Martin, Sandra L., et al.
Publicado: (2008)

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night
por: deHaro, Dawn, et al.
Publicado: (2014)

L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodeling
por: Naufer, M. Nabuan, et al.
Publicado: (2016)

The N-terminal 33 amino acid domain of Siva-1 is sufficient for nuclear localization
por: Chen, J.Y., et al.
Publicado: (2013)

Iodothyronine Interactions with the System L1 Amino Acid Exchanger in 3T3-L1 Adipocytes
por: Mitchell, Fiona E., et al.
Publicado: (2010)

Organ-, sex- and age-dependent patterns of endogenous L1 mRNA expression at a single locus resolution
por: Stow, Emily C, et al.
Publicado: (2021)

Disruption of PML Nuclear Bodies Is Mediated by ORF61 SUMO-Interacting Motifs and Required for Varicella-Zoster Virus Pathogenesis in Skin
por: Wang, Li, et al.
Publicado: (2011)

The ORF1 Protein Encoded by LINE-1: Structure and Function During L1 Retrotransposition
por: Martin, Sandra L.
Publicado: (2006)

Equid alphaherpesvirus 1 from Italian Horses: Evaluation of the Variability of the ORF30, ORF33, ORF34 and ORF68 Genes
por: Preziuso, Silvia, et al.
Publicado: (2019)

Polymerization and nucleic acid-binding properties of human L1 ORF1 protein
por: Callahan, Kathryn E., et al.
Publicado: (2012)

Analysis of epigenetic features characteristic of L1 loci expressed in human cells
por: Freeman, Benjamin, et al.
Publicado: (2022)

Further Requirements for Cleavage by the Murine Coronavirus 3C-like Proteinase: Identification of a Cleavage Site within ORF1b
por: Piñón, Josefina D., et al.
Publicado: (1999)

Identification of the nuclear localization signal in the Saccharomyces cerevisiae Pif1 DNA helicase
por: Lee, Rosemary S., et al.
Publicado: (2023)

Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics
por: Wallace, Nicholas A, et al.
Publicado: (2010)

Nuclear Localization of HopA1(Pss61) Is Required for Effector-Triggered Immunity
por: Kang, Hobin, et al.
Publicado: (2021)

Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization
por: Koutroumani, Maria, et al.
Publicado: (2017)

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels
por: Xiao, Shangxi, et al.
Publicado: (2019)

Expression of the hepatitis E virus ORF1
por: Ropp, S. L., et al.
Publicado: (2000)

THE AMINO ACID REQUIREMENTS OF MONKEY KIDNEY CELLS IN FIRST CULTURE PASSAGE
por: Eagle, Harry, et al.
Publicado: (1958)

Cannot write session to /tmp/vufind_sessions/sess_0tee51t08mnmpn7fcq2pq3p0i3