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CXCR4-targeted liposomal mediated co-delivery of pirfenidone and AMD3100 for the treatment of TGFβ-induced HSC-T6 cells activation

Background: Liver fibrosis is a chronic liver disease associated with an excessive accumulation of extracellualr matrix (ECM) proteins which ultimately lead to cirrohosis and hepatocellular carcinoma. Purpose: Liver fibrosis therapies that use combination approaches with the ability to affect multip...

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Detalles Bibliográficos
Autores principales: Ullah, Aftab, Wang, Kaikai, Wu, Pengkai, Oupicky, David, Sun, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501422/
https://www.ncbi.nlm.nih.gov/pubmed/31118614
http://dx.doi.org/10.2147/IJN.S171280