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Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma

Background: Sufficient supply of deoxyribonucleoside triphosphates (dNTPs) is required for the uncontrolled replication of cancers. The current study aimed to investigate the biological and clinical role of ribonucleotide reductase subunit M2 (RRM2), a key enzyme regulating the dNTP pool, in clear-c...

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Detalles Bibliográficos
Autores principales: Zou, Yun, Zhou, Juan, Xu, Bin, Li, Wenzhi, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501780/
https://www.ncbi.nlm.nih.gov/pubmed/31118677
http://dx.doi.org/10.2147/OTT.S196347