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Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma
Background: Sufficient supply of deoxyribonucleoside triphosphates (dNTPs) is required for the uncontrolled replication of cancers. The current study aimed to investigate the biological and clinical role of ribonucleotide reductase subunit M2 (RRM2), a key enzyme regulating the dNTP pool, in clear-c...
Autores principales: | Zou, Yun, Zhou, Juan, Xu, Bin, Li, Wenzhi, Wang, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501780/ https://www.ncbi.nlm.nih.gov/pubmed/31118677 http://dx.doi.org/10.2147/OTT.S196347 |
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