A complex containing lysine-acetylated actin inhibits the formin INF2

INF2 is a member of the formin family of actin assembly factors. Dominant mis-sense mutations in INF2 link to two diseases: focal segmental glomerulosclerosis (FSGS), a kidney disease; and Charcot-Marie-Tooth disease (CMTD), a neuropathy. All disease mutations map to the autoinhibitory Diaphanous In...

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Detalles Bibliográficos
Autores principales: Mu, A, Fung, Tak Shun, Kettenbach, Arminja N., Chakrabarti, Rajarshi, Higgs, Henry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501848/
https://www.ncbi.nlm.nih.gov/pubmed/30962575
http://dx.doi.org/10.1038/s41556-019-0307-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501848/
https://www.ncbi.nlm.nih.gov/pubmed/30962575
http://dx.doi.org/10.1038/s41556-019-0307-4

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