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A complex containing lysine-acetylated actin inhibits the formin INF2
INF2 is a member of the formin family of actin assembly factors. Dominant mis-sense mutations in INF2 link to two diseases: focal segmental glomerulosclerosis (FSGS), a kidney disease; and Charcot-Marie-Tooth disease (CMTD), a neuropathy. All disease mutations map to the autoinhibitory Diaphanous In...
Autores principales: | Mu, A, Fung, Tak Shun, Kettenbach, Arminja N., Chakrabarti, Rajarshi, Higgs, Henry N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501848/ https://www.ncbi.nlm.nih.gov/pubmed/30962575 http://dx.doi.org/10.1038/s41556-019-0307-4 |
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