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Phosphodiesterase-induced cAMP degradation restricts hepatitis B virus infection

Hepatitis B virus (HBV) entry into hepatocytes is mediated via a high-affinity interaction between the preS1 glycoprotein and sodium/bile acid cotransporting polypeptide (NTCP). To date, in vitro model systems rely on high multiplicities of infection to achieve infection of cell lines overexpressing...

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Detalles Bibliográficos
Autores principales: Evripioti, Antonia Alexandra, Ortega-Prieto, Ana Maria, Skelton, Jessica Katy, Bazot, Quentin, Dorner, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501904/
https://www.ncbi.nlm.nih.gov/pubmed/30955495
http://dx.doi.org/10.1098/rstb.2018.0292