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Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis

BACKGROUND: Chronic kidney disease (CKD) is defined by abnormalities in kidney structure and/or function present for more than 3 months. Worldwide, both the incidence and prevalence rates of CKD are increasing. The renin-angiotensin-aldosterone system (RAAS) regulates fluid and electrolyte balance t...

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Detalles Bibliográficos
Autores principales: Smyth, Laura Jane, Cañadas-Garre, Marisa, Cappa, Ruaidhri C, Maxwell, Alexander P, McKnight, Amy Jayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501980/
https://www.ncbi.nlm.nih.gov/pubmed/31048445
http://dx.doi.org/10.1136/bmjopen-2018-026777