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Botulinum toxin treatment of spasticity targeted to muscle endplates: an international, randomised, evaluator-blinded study comparing two different botulinum toxin injection strategies for the treatment of upper limb spasticity

OBJECTIVES: The therapeutic effects of botulinum neurotoxin (BoNT) are well documented in upper limb spasticity. However, several factors may influence treatment efficacy, including targeting of neuromuscular junctions (NMJs). We examined whether NMJ-targeted BoNT injections were non-inferior, in te...

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Detalles Bibliográficos
Autores principales: Rekand, Tiina, Biering-Sörensen, Bo, He, Jun, Vilholm, Ole Jakob, Christensen, Peter Brøgger, Ulfarsson, Trandur, Belusa, Roger, Ström, Torbjörn, Myrenfors, Peter, Maisonobe, Pascal, Dalager, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502046/
https://www.ncbi.nlm.nih.gov/pubmed/31061021
http://dx.doi.org/10.1136/bmjopen-2018-024340