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The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin

Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin disease resulting in non-healing wounds affecting body areas of high hair follicle and sweat gland density. The pathogenesis of HS is not well understood but appears to involve dysbiosis-driven aberrant activation of the innat...

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Detalles Bibliográficos
Autores principales: Coates, Margaret, Mariottoni, Paula, Corcoran, David L., Kirshner, Hélène Fradin, Jaleel, Tarannum, Brown, David A., Brooks, Stephen R., Murray, John, Morasso, Maria I., MacLeod, Amanda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502346/
https://www.ncbi.nlm.nih.gov/pubmed/31059533
http://dx.doi.org/10.1371/journal.pone.0216249