Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection

Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenesis, but the immune mechanisms that noroviruses exp...

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Detalles Bibliográficos
Autores principales: Dubois, Hanne, Sorgeloos, Frederic, Sarvestani, Soroush T., Martens, Liesbet, Saeys, Yvan, Mackenzie, Jason M., Lamkanfi, Mohamed, van Loo, Geert, Goodfellow, Ian, Wullaert, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502405/
https://www.ncbi.nlm.nih.gov/pubmed/31017981
http://dx.doi.org/10.1371/journal.ppat.1007709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502405/
https://www.ncbi.nlm.nih.gov/pubmed/31017981
http://dx.doi.org/10.1371/journal.ppat.1007709

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