Cargando…

LINE-1 hypomethylation in human hepatocellular carcinomas correlates with shorter overall survival and CIMP phenotype

Reactivation of interspersed repetitive sequences due to loss of methylation is associated with genomic instability, one of the hallmarks of cancer cells. LINE-1 hypomethylation is a surrogate marker for global methylation loss and is potentially a new diagnostic and prognostic biomarker in tumors....

Descripción completa

Detalles Bibliográficos
Autores principales:	Anwar, Sumadi Lukman, Hasemeier, Britta, Schipper, Elisa, Vogel, Arndt, Kreipe, Hans, Lehmann, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502450/ https://www.ncbi.nlm.nih.gov/pubmed/31059558 http://dx.doi.org/10.1371/journal.pone.0216374

Ejemplares similares

Loss of Imprinting and Allelic Switching at the DLK1-MEG3 Locus in Human Hepatocellular Carcinoma
por: Anwar, Sumadi Lukman, et al.
Publicado: (2012)

Loss of DNA methylation at imprinted loci is a frequent event in hepatocellular carcinoma and identifies patients with shortened survival
por: Anwar, Sumadi Lukman, et al.
Publicado: (2015)

hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma
por: Anwar, Sumadi Lukman, et al.
Publicado: (2017)

Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.
por: Roessler, Jessica, et al.
Publicado: (2012)

Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms
por: Bartels, Stephan, et al.
Publicado: (2016)

MicroRNAs: Emerging Novel Clinical Biomarkers for Hepatocellular Carcinomas
por: Anwar, Sumadi Lukman, et al.
Publicado: (2015)

Reliable microRNA profiling in routinely processed formalin-fixed paraffin-embedded breast cancer specimens using fluorescence labelled bead technology
por: Hasemeier, Britta, et al.
Publicado: (2008)

Identification of differentially expressed microRNAs in human male breast cancer
por: Lehmann, Ulrich, et al.
Publicado: (2010)

Extrathyroidal extension and cervical node infiltration are associated with recurrences and shorter recurrence-free survival in differentiated thyroid cancer: a cohort study
por: Anwar, Sumadi Lukman, et al.
Publicado: (2022)

Transposable Elements in Human Cancer: Causes and Consequences of Deregulation
por: Anwar, Sumadi Lukman, et al.
Publicado: (2017)

18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high
por: Ogino, Shuji, et al.
Publicado: (2007)

Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution
por: Potapova, Anna, et al.
Publicado: (2011)

The CpG island methylator phenotype (CIMP) in colorectal cancer
por: Mojarad, Ehsan Nazemalhosseini, et al.
Publicado: (2013)

Development and validation of a CIMP-associated prognostic model for hepatocellular carcinoma
por: Li, Ganxun, et al.
Publicado: (2019)

The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma
por: Fedorova, Maria S., et al.
Publicado: (2019)

Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers
por: Chong, Allen, et al.
Publicado: (2016)

Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
por: Flatin, Bjørnar T.B., et al.
Publicado: (2020)

Comprehensive Molecular Profiling of Archival Bone Marrow Trephines Using a Commercially Available Leukemia Panel and Semiconductor-Based Targeted Resequencing
por: Bartels, Stephan, et al.
Publicado: (2015)

Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system
por: Bae, Jeong Mo, et al.
Publicado: (2017)

Expression and regulatory roles of lncRNAs in G-CIMP-low vs G-CIMP-high Glioma: an in-silico analysis
por: Datta, Indrani, et al.
Publicado: (2021)

Comment on ‘Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system’
por: Tapial, Sandra, et al.
Publicado: (2018)

Reply to ‘Comment on ‘Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system”
por: Bae, Jeong Mo, et al.
Publicado: (2018)

The CIMP Phenotype in BRAF Mutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort
por: Fernando, Winnie C., et al.
Publicado: (2014)

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas
por: Li, Jie, et al.
Publicado: (2014)

The Emergence of Pan-Cancer CIMP and Its Elusive Interpretation
por: Miller, Brendan F., et al.
Publicado: (2016)

Is Upregulation of BCL2 a Determinant of Tumor Development Driven by Inactivation of CDH1/E-Cadherin?
por: Karch, Inga, et al.
Publicado: (2013)

Radiofrequency ablation for management of thyroid nodules in quarantine zone of COVID-19 pandemic setting in Indonesia
por: Yarso, Kristanto Yuli, et al.
Publicado: (2022)

Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer
por: Liu, Jiang, et al.
Publicado: (2019)

Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs
por: Anwar, Sumadi Lukman, et al.
Publicado: (2017)

Body Size, Physical Activity and Risk of Colorectal Cancer with or without the CpG Island Methylator Phenotype (CIMP)
por: Hughes, Laura A. E., et al.
Publicado: (2011)

Differentiating Chilaiditi’s Syndrome with hollow viscus perforation: A case report
por: Sofii, Imam, et al.
Publicado: (2020)

Perspectives on how to navigate cancer surgery in the breast, head and neck, skin, and soft tissue tumor in limited-resource countries during COVID-19 pandemic
por: Anwar, Sumadi Lukman, et al.
Publicado: (2020)

The development of early ascites is associated with shorter overall survival in patients with hepatocellular carcinoma treated with drug-eluting embolic chemoembolization
por: Pipa-Muñiz, María, et al.
Publicado: (2020)

cIMP: Synthesis, effector activation, inactivation and occurrence in biological systems
por: Seifert, Roland, et al.
Publicado: (2015)

Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas
por: Yin, An-An, et al.
Publicado: (2019)

CIMP-positive glioma is associated with better prognosis: A systematic analysis
por: Xu, Yingying, et al.
Publicado: (2022)

Clinicopathological and Molecular Profiles of Sporadic Microsatellite Unstable Colorectal Cancer with or without the CpG Island Methylator Phenotype (CIMP)
por: Chang, Shih-Ching, et al.
Publicado: (2020)

Kidney tumors associated with germline mutations of FH and SDHB show a CpG island methylator phenotype (CIMP)
por: Ricketts, Christopher J., et al.
Publicado: (2022)

Polymorphisms of brain-derived neurotrophic factor genes are associated with anxiety and body mass index in fibromyalgia syndrome patients
por: Nugraha, Boya, et al.
Publicado: (2020)

ATM/RB1 mutations predict shorter overall survival in urothelial cancer
por: Yin, Ming, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9o7l4qv4iov4r3jqb8s77h3t8k