Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification

BACKGROUND: A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. Heterogeneous intratumor gene expression in GBM is well documented, but littl...

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Detalles Bibliográficos
Autores principales: Wenger, Anna, Ferreyra Vega, Sandra, Kling, Teresia, Bontell, Thomas Olsson, Jakola, Asgeir Store, Carén, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502500/
https://www.ncbi.nlm.nih.gov/pubmed/30668814
http://dx.doi.org/10.1093/neuonc/noz011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502500/
https://www.ncbi.nlm.nih.gov/pubmed/30668814
http://dx.doi.org/10.1093/neuonc/noz011

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