Cargando…
Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification
BACKGROUND: A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. Heterogeneous intratumor gene expression in GBM is well documented, but littl...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502500/ https://www.ncbi.nlm.nih.gov/pubmed/30668814 http://dx.doi.org/10.1093/neuonc/noz011 |