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RGMB enhances the suppressive activity of the monomeric secreted form of CTLA-4
The immunoregulatory molecule CTLA-4 plays a crucial role in the maintenance of immune homeostasis. CTLA-4-neutralizing antibodies are now approved for the treatment of advanced melanoma, and are in development for treating other cancers as well. However, a thorough understanding of CTLA-4 function...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502797/ https://www.ncbi.nlm.nih.gov/pubmed/31061392 http://dx.doi.org/10.1038/s41598-019-43068-y |