Structural basis of substrate recognition by a novel thermostable (S)-enantioselective ω-transaminase from Thermomicrobium roseum

Transaminases catalyze the reversible transfer reaction of an amino group between a primary amine and an α-keto acid, utilizing pyridoxal 5′-phosphate as a cofactor. ω-transaminases (ωTAs) recognize an amino group linked to a non-α carbon of amine substrates. Recently, a novel (S)-enantioselective ω...

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Detalles Bibliográficos
Autores principales: Kwon, Sunghark, Lee, Jun Hyuck, Kim, Chang Min, Jang, Hyunseok, Yun, Hyungdon, Jeon, Ju-Hong, So, Insuk, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502798/
https://www.ncbi.nlm.nih.gov/pubmed/31061438
http://dx.doi.org/10.1038/s41598-019-43490-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502798/
https://www.ncbi.nlm.nih.gov/pubmed/31061438
http://dx.doi.org/10.1038/s41598-019-43490-2

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