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The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

Translation and transcription are frequently dysregulated in cancer. These two processes are generally regulated by distinct sets of factors. The CBFB gene, which encodes a transcription factor, has recently emerged as a highly mutated driver in a variety of human cancers including breast cancer. He...

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Detalles Bibliográficos
Autores principales: Malik, Navdeep, Yan, Hualong, Moshkovich, Nellie, Palangat, Murali, Yang, Howard, Sanchez, Vanesa, Cai, Zhuo, Peat, Tyler J., Jiang, Shunlin, Liu, Chengyu, Lee, Maxwell, Mock, Beverly A., Yuspa, Stuart H., Larson, Daniel, Wakefield, Lalage M., Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502810/
https://www.ncbi.nlm.nih.gov/pubmed/31061501
http://dx.doi.org/10.1038/s41467-019-10102-6