Deleterious effects of formalin-fixation and delays to fixation on RNA and miRNA-Seq profiles

The National Cancer Institute conducted the Biospecimen Pre-analytical Variables (BPV) study to determine the effects of formalin fixation and delay to fixation (DTF) on the analysis of nucleic acids. By performing whole transcriptome sequencing and small RNA profiling on matched snap-frozen and FFP...

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Detalles Bibliográficos
Autores principales: Jones, Wendell, Greytak, Sarah, Odeh, Hana, Guan, Ping, Powers, Jason, Bavarva, Jasmin, Moore, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502812/
https://www.ncbi.nlm.nih.gov/pubmed/31061401
http://dx.doi.org/10.1038/s41598-019-43282-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502812/
https://www.ncbi.nlm.nih.gov/pubmed/31061401
http://dx.doi.org/10.1038/s41598-019-43282-8

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