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Deleterious effects of formalin-fixation and delays to fixation on RNA and miRNA-Seq profiles
The National Cancer Institute conducted the Biospecimen Pre-analytical Variables (BPV) study to determine the effects of formalin fixation and delay to fixation (DTF) on the analysis of nucleic acids. By performing whole transcriptome sequencing and small RNA profiling on matched snap-frozen and FFP...
Autores principales: | Jones, Wendell, Greytak, Sarah, Odeh, Hana, Guan, Ping, Powers, Jason, Bavarva, Jasmin, Moore, Helen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502812/ https://www.ncbi.nlm.nih.gov/pubmed/31061401 http://dx.doi.org/10.1038/s41598-019-43282-8 |
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