Identifying immunologically-vulnerable regions of the HCV E2 glycoprotein and broadly neutralizing antibodies that target them

Isolation of broadly neutralizing human monoclonal antibodies (HmAbs) targeting the E2 glycoprotein of Hepatitis C virus (HCV) has sparked hope for effective vaccine development. Nonetheless, escape mutations have been reported. Ideally, a potent vaccine should elicit HmAbs that target regions of E2...

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Detalles Bibliográficos
Autores principales: Quadeer, Ahmed A., Louie, Raymond H. Y., McKay, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502829/
https://www.ncbi.nlm.nih.gov/pubmed/31061402
http://dx.doi.org/10.1038/s41467-019-09819-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502829/
https://www.ncbi.nlm.nih.gov/pubmed/31061402
http://dx.doi.org/10.1038/s41467-019-09819-1

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