Cargando…

RNA m(6)A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

N6-Methyladenosine (m(6)A) modification has been implicated in the progression of several cancers. We reveal that during epithelial-mesenchymal transition (EMT), one important step for cancer cell metastasis, m(6)A modification of mRNAs increases in cancer cells. Deletion of methyltransferase-like 3...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Xinyao, Chai, Guoshi, Wu, Yingmin, Li, Jiexin, Chen, Feng, Liu, Jianzhao, Luo, Guanzheng, Tauler, Jordi, Du, Jun, Lin, Shuibin, He, Chuan, Wang, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502834/
https://www.ncbi.nlm.nih.gov/pubmed/31061416
http://dx.doi.org/10.1038/s41467-019-09865-9