Cargando…

The structural arrangement at intersubunit interfaces in homomeric kainate receptors

Kainate receptors are glutamate-gated cation-selective channels involved in excitatory synaptic signaling and are known to be modulated by ions. Prior functional and structural studies suggest that the dimer interface at the agonist-binding domain plays a key role in activation, desensitization, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Litwin, Douglas B., Carrillo, Elisa, Shaikh, Sana A., Berka, Vladimir, Jayaraman, Vasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502836/
https://www.ncbi.nlm.nih.gov/pubmed/31061516
http://dx.doi.org/10.1038/s41598-019-43360-x