Cargando…
Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors
Hydride transfers play a crucial role in a multitude of biological redox reactions and are mediated by flavin, deazaflavin or nicotinamide adenine dinucleotide cofactors at standard redox potentials ranging from 0 to –340 mV. 2-Naphthoyl-CoA reductase, a key enzyme of oxygen-independent bacterial na...
Autores principales: | Willistein, Max, Bechtel, Dominique F., Müller, Christina S., Demmer, Ulrike, Heimann, Larissa, Kayastha, Kanwal, Schünemann, Volker, Pierik, Antonio J., Ullmann, G. Matthias, Ermler, Ulrich, Boll, Matthias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502838/ https://www.ncbi.nlm.nih.gov/pubmed/31061390 http://dx.doi.org/10.1038/s41467-019-10078-3 |
Ejemplares similares
-
Structural Basis of Cyclic 1,3‐Diene Forming Acyl‐Coenzyme A Dehydrogenases
por: Kung, Johannes W., et al.
Publicado: (2021) -
Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis
por: Giancaspero, Teresa A., et al.
Publicado: (2015) -
The structural and functional roles of the flavin cofactor FAD in mammalian cryptochromes
por: Calloni, Giulia, et al.
Publicado: (2023) -
Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis
por: Moreno, Andrea, et al.
Publicado: (2021) -
The FAD Cofactor of RebC Shifts to an IN Conformation upon Flavin Reduction(,)
por: Ryan, Katherine S., et al.
Publicado: (2008)