Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota

Our pilot study suggested that orally administered crocin was hardly absorbed into circulatory system, but it was effective against cerebral ischemic/reperfusion (I/R) injury. The pharmacologically active component and targeting site of crocin remain elusive. In this study, the cerebral-protective e...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Geng, Jianliang, Hong, Yu, Jiao, Li, Li, Shuning, Sun, Runbin, Xie, Yuan, Yan, Caixia, Aa, Jiye, Wang, Guangji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502977/
https://www.ncbi.nlm.nih.gov/pubmed/31114499
http://dx.doi.org/10.3389/fphar.2019.00440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502977/
https://www.ncbi.nlm.nih.gov/pubmed/31114499
http://dx.doi.org/10.3389/fphar.2019.00440

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