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Functional analysis of haplotypes and promoter activity at the 5′ region of the human GABRB3 gene and associations with schizophrenia

BACKGROUND: This study investigated the effects of haplotypes T‐G and C‐A derived from NG_012836.1:g.4160T>C and NG_012836.1:g.4326G>A on protein expression levels in vitro and identified the functional sequence in the regulatory region of the GABRB3 gene linked to possible associations with s...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Ding, Mei, Liu, Yong‐ping, Zhang, Xi‐cen, Xing, Jia‐xin, Xuan, Jin‐feng, Xia, Xi, Yao, Jun, Wang, Bao‐jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503024/
https://www.ncbi.nlm.nih.gov/pubmed/30908890
http://dx.doi.org/10.1002/mgg3.652