Cargando…

Sodium Benzoate Attenuates Secondary Brain Injury by Inhibiting Neuronal Apoptosis and Reducing Mitochondria-Mediated Oxidative Stress in a Rat Model of Intracerebral Hemorrhage: Possible Involvement of DJ-1/Akt/IKK/NFκB Pathway

Intracerebral hemorrhage (ICH) is a devastating disease with high rates of mortality and morbidity. The aim of this study was to explore whether Sodium Benzoate (NaB) could reduce neural cell apoptosis and alleviate neurological deficits after ICH. To assess the therapeutic effects of NaB, first, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Weilin, Li, Tao, Gao, Liansheng, Lenahan, Cameron, Zheng, Jingwei, Yan, Jun, Shao, Anwen, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503040/
https://www.ncbi.nlm.nih.gov/pubmed/31114478
http://dx.doi.org/10.3389/fnmol.2019.00105