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Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts

[Image: see text] A targeted ultrahigh-performance liquid chromatography tandem mass spectrometry with electrospray ionization (UHPLC-ESI-MS/MS) method has been developed for the quantification of tryptophan and its downstream metabolites from the kynurenine and serotonin pathways. The assay coverag...

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Detalles Bibliográficos
Autores principales: Whiley, Luke, Nye, Leanne C., Grant, Isobelle, Andreas, Nick, Chappell, Katie E., Sarafian, Magali H., Misra, Ravi, Plumb, Robert S., Lewis, Matthew R., Nicholson, Jeremy K., Holmes, Elaine, Swann, Jonathan R., Wilson, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503468/
https://www.ncbi.nlm.nih.gov/pubmed/30848589
http://dx.doi.org/10.1021/acs.analchem.8b05884