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The Use of Molecular Descriptors To Model Pharmaceutical Uptake by a Fish Primary Gill Cell Culture Epithelium

[Image: see text] Modeling approaches such as quantitative structure–activity relationships (QSARs) use molecular descriptors to predict the bioavailable properties of a compound in biota. However, these models have mainly been derived based on empirical data for lipophilic neutral compounds and may...

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Detalles Bibliográficos
Autores principales: Chang, Elisabeth D., Hogstrand, Christer, Miller, Thomas H., Owen, Stewart F., Bury, Nic R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503469/
https://www.ncbi.nlm.nih.gov/pubmed/30589539
http://dx.doi.org/10.1021/acs.est.8b04394