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Abatacept induced granulomatous hepatitis with a sarcoidosis- like reaction: a blinded trial in mice
BACKGROUND: Abatacept is increasingly used for rheumatoid arthritis (RA) and juvenile idiophathic arthritis (JIA) treatment. However little is known about the risk of hepatotoxicity. The aim of this study was to determine whether the inhibition of the T cell CD28 receptor by abatacept results in acu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503540/ https://www.ncbi.nlm.nih.gov/pubmed/31064410 http://dx.doi.org/10.1186/s40360-019-0303-0 |