Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice

Tau is a microtubule stabilizing protein that forms aggregates in Alzheimer’s disease (AD). Tau derived from AD patients’ brains induces tau aggregation in a prion-like manner when injected into susceptible mouse models. Here we investigated whether cerebrospinal fluid (CSF) collected from patients...

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Detalles Bibliográficos
Autores principales: Skachokova, Zhiva, Martinisi, Alfonso, Flach, Martin, Sprenger, Frederik, Naegelin, Yvonne, Steiner-Monard, Viviane, Sollberger, Marc, Monsch, Andreas U., Goedert, Michel, Tolnay, Markus, Winkler, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503541/
https://www.ncbi.nlm.nih.gov/pubmed/31064413
http://dx.doi.org/10.1186/s40478-019-0725-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503541/
https://www.ncbi.nlm.nih.gov/pubmed/31064413
http://dx.doi.org/10.1186/s40478-019-0725-3

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