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Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice

Tau is a microtubule stabilizing protein that forms aggregates in Alzheimer’s disease (AD). Tau derived from AD patients’ brains induces tau aggregation in a prion-like manner when injected into susceptible mouse models. Here we investigated whether cerebrospinal fluid (CSF) collected from patients...

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Detalles Bibliográficos
Autores principales:	Skachokova, Zhiva, Martinisi, Alfonso, Flach, Martin, Sprenger, Frederik, Naegelin, Yvonne, Steiner-Monard, Viviane, Sollberger, Marc, Monsch, Andreas U., Goedert, Michel, Tolnay, Markus, Winkler, David T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503541/ https://www.ncbi.nlm.nih.gov/pubmed/31064413 http://dx.doi.org/10.1186/s40478-019-0725-3

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