BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients

BET bromodomain proteins are important epigenetic regulators of gene expression that bind acetylated histone tails and regulate the formation of acetylation-dependent chromatin complexes. BET inhibitors suppress inflammatory responses in multiple cell types and animal models, and protect against bon...

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Detalles Bibliográficos
Autores principales: Maksylewicz, Anna, Bysiek, Agnieszka, Lagosz, Katarzyna B., Macina, Justyna M., Kantorowicz, Malgorzata, Bereta, Grzegorz, Sochalska, Maja, Gawron, Katarzyna, Chomyszyn-Gajewska, Maria, Potempa, Jan, Grabiec, Aleksander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503739/
https://www.ncbi.nlm.nih.gov/pubmed/31114581
http://dx.doi.org/10.3389/fimmu.2019.00933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503739/
https://www.ncbi.nlm.nih.gov/pubmed/31114581
http://dx.doi.org/10.3389/fimmu.2019.00933

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