Cargando…

Quantifying local malignant adaptation in tissue‐specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level

Cancer is a potentially lethal disease, in which patients with nearly identical genetic backgrounds can develop a similar pathology through distinct combinations of genetic alterations. We aimed to reconstruct the evolutionary process underlying tumour initiation, using the combination of convergenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Tokutomi, Natsuki, Moyret‐Lalle, Caroline, Puisieux, Alain, Sugano, Sumio, Martinez, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503823/
https://www.ncbi.nlm.nih.gov/pubmed/31080515
http://dx.doi.org/10.1111/eva.12781